A label-free DNA reduced graphene oxide-based fluorescent sensor for highly sensitive and selective detection of hemin.
نویسندگان
چکیده
G-quadruplex structure aptamer (PS2.M) can capture acridine orange (AO) from reduced graphene oxide (rGO). When the AO-PS2.M/rGO mixture is incubated with hemin, the specific binding of hemin with PS2.M results in a release of AO from PS2.M and return of AO back to rGO. Based on the quenching of fluorescence, the target hemin was detected sensitively and selectively, giving a detection limit of 50 nM.
منابع مشابه
Highly Sensitive Amperometric Sensor Based on Gold Nanoparticles Polyaniline Electrochemically Reduced Graphene Oxide Nanocomposite for Detection of Nitric Oxide
A sensitive electrochemical sensor was fabricated for selective detection of nitric oxide (NO) based on electrochemically reduced graphene (ErGO)-polyaniline (PANI)-gold nanoparticles (AuNPs) nanocomposite. It was coated on a gold (Au) electrode through stepwise electrodeposition to form AuNPs-PANI-ErGO/Au electrode. The AuNPs-PANI-rGO nanocomposite was characterized by Field Emission Scanning ...
متن کاملGraphene Oxide-terpyridine Conjugate: A Highly Selective Colorimetric and Sensitive Fluorescence Nano-chemosensor for Fe2+ in Aqueous Media
A graphene oxide-terpyridine conjugate (GOTC) based colorimetric and fluorescent nano-chemosensor was synthesized. It showed high selectivity and sensitivity for Fe2+ and Fe3+ ions in neutral aqueous solution over other metal ions such as Li+, Na+, Ba2+, Ca2+, Al3+, Cd2+, Co2+, Cu2+, Hg2+, Mn...
متن کاملInvestigation of immunosensor modification with reduced Graphene Oxide with Au Nanoparticles on glassy carbon electrode in Label-free for Escherichia coli detection
Escherichia coli is an indicator in the quality control of pharmaceutical and other samples. Reduced graphene oxide (rGO) as a kind of carbon compositions was immobilized on glassy carbon electrode (GCE). Chronoamperometric and reduction methods were used for Au NPs decoration and it completed with polyclonal E. coli antibody and 0.5 W/V% Bovine Serum Albumin solution. Morphology and structure ...
متن کاملA reversible fluorescence nanoswitch based on bifunctional reduced graphene oxide: use for detection of Hg2+ and molecular logic gate operation.
Herein, we demonstrate the first use of a reduced graphene oxide (rGO)-organic dye nanoswitch for the label-free, sensitive and selective detection of Hg(2+) using bifunctional rGO as an effective nanoquencher and highly selective nanosorbent. Moreover, a reversible on-off INHIBIT rGO logic gate based on a cysteine-Hg(2+) system has also been designed.
متن کاملGraphene Oxide/Polyaniline-Based Multi Nano Sensor for Simultaneous Detection of Carbon Dioxide, Methane, Ethanol and Ammonia Gases
In this study, a multi nanosensor was fabricated for the simultaneous detection of carbon dioxide, methane, ethanol, and ammonia gases, and its electrochemical response to various concentrations of these gases were investigated. In order to fabricate this multi nanosensor, in the first phase, the Graphene-Oxide/Polyaniline (GO/PANI) nanocomposite was synthesized. Chemical ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Chemical communications
دوره 47 16 شماره
صفحات -
تاریخ انتشار 2011